Home       How it works     Search Cruises     Browse Ships     Group Cruises     Cruise Specials     Colon Cruise Departures Cruises that depart from Central America: Panama: Colon Cruises that visit Colon Below are cruise ship itineraries sailing from Colon. Click on an itinerary then select a sail date to request competing price quotes from independent cruise travel agents. Compare the offers, then contact the agents directly for more information or to book. To search through all cruise itineraries (not just Colon) to compare multiple, competing quotes from independent cruise travel agents, please visit our Cruise Search page. Royal Caribbean (RCL), RCL Enchantment of the Seas   7 Night Southern Caribbean Cruise 7 Days - Starting in Colon with stops in Cartagena, Santa Marta, Oranjestad, Willemstad, Kralendijk, Cruising 2008 Sails: Dec 7, Dec 14, 2009: Jan 4, Jan 11, Jan 18, Jan 25, Feb 1, Feb 8, Feb 15, Feb 22, Mar 1, Mar 8, Mar 15, Mar 22, Mar 29, Apr 5, Apr 12   Royal Caribbean (RCL), RCL Enchantment of the Seas   7 Night Southern Caribbean Cruise 7 Days - Starting in Colon with stops in Cartagena, Santa Marta, Oranjestad, Willemstad, Kralendijk, Cruising 2008 Sails: Dec 21, Dec 28   Royal Caribbean (RCL), RCL Enchantment of the Seas   8 Night Southern Caribbean Cruise 8 Days - Starting in Colon with stops in Puerto Limon, Cruising, Cartagena, Santa Marta, Oranjestad, Fort Lauderdale 2009 Sails: Apr 19   Royal Caribbean (RCL), RCL Enchantment of the Seas   7 Night Southern Caribbean Cruise 7 Days - Starting in Colon with stops in Cartagena, Santa Marta, Oranjestad, Willemstad, Kralendijk, Cruising 2009 Sails: Dec 6, Dec 13, 2010: Jan 3, Jan 10, Jan 17, Jan 24, Jan 31, Feb 7, Feb 14, Feb 21, Feb 28, Mar 7, Mar 14, Mar 21, Mar 28, Apr 4   Royal Caribbean (RCL), RCL Enchantment of the Seas   7 Night Southern Caribbean Cruise 7 Days - Starting in Colon with stops in Cartagena, Santa Marta, Oranjestad, Willemstad, Cruising, Puerto Limon 2009 Sails: Dec 20, Dec 27   Royal Caribbean (RCL), RCL Enchantment of the Seas   8 Night Southern Caribbean Cruise 8 Days - Starting in Colon with stops in Puerto Limon, Cruising, Cartagena, Santa Marta, Oranjestad, Fort Lauderdale 2010 Sails: Apr 11   Colon Cruise Departures   Your Account :: Home :: Search :: Specials :: Cruises :: Discount Airfare :: About :: FAQ Cruise departures:  Miami   Fort Lauderdale   Port Canaveral   Los Angeles   Vancouver   San Juan   San Diego   Seattle   New York   Tampa   Galveston   New Orleans   Jacksonville   Mobile   Baltimore   Seward   Honolulu   Boston   Whittier   San Francisco   Cape Liberty   Charleston   Cape Liberty Port   Charlotte Amalie   St Thomas   Montreal   Norfolk   Anchorage   Philadelphia   San Jose  Browse Cruise Lines  Amadeus Waterways   Avalon Waterways   Azamara Cruises   Carnival Cruises   Celebrity Cruises   Costa Cruises   Crystal Cruises   Cunard   Discovery World Cruises   Disney Cruises   Festiva Sailing Vacations   Holland America (HAL)   Imperial Travel   Island Cruises   Majestic America Line   MSC Italian   Norwegian Cruise Line (NCL)   Ocean Village   Oceania Cruises   P & O Cruises   Princess Cruises   Regent Seven Seas   Royal Caribbean (RCL)   Seabourn   SeaDream Yacht Club   Silversea   Star Clippers   Star Cruises   Steps of Paul Cruises   Swan Hellenic Cruises   Thomson Cruises   Uniworld   Viking River   Windstar Cruises   Cruises by Region Try ResortCompete.com for competing quotes on all-inclusive resorts.