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Ohio River Cruise Departures

River Cruises that depart from North America: United States: Ohio

River Cruises that visit Ohio

Below are river cruise ship itineraries sailing from Ohio. Click on an itinerary then select a sail date to receive multiple custom cruise options to compare. Compare the offers, then contact the agents directly for more information or to book. To search through all river cruise itineraries (not just Ohio), please visit our Cruise Search page.

Related areas: Cincinnati

American Cruise Lines, Queen of the Mississippi
Queen of the Mississippi Cruises   7 Night Ohio River Cruise from Cincinnati, OH to Memphis, TN
7 Days - Starting in Cincinnati, OH; with stops in Madison, IN; Louisville, KY; Henderson, KY; Paducah, KY; New Madrid, MO; Memphis, TN
2016 Sails: Jul 2, More...
American Queen Steamboat Company, American Queen
American Queen Cruises   9 Day Ohio and Tennessee Rivers Presidents and Politics from Cincinnati to St. Louis
9 Days - Starting in Cincinnati, OH; with stops in Louisville, KY; Bradenburg, KY; Henderson, KY; Paducah, KY; Cape Girardeau, MO; Alton, IL
2016 Sails: Jul 17, More...

Ohio River Cruise Departures

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